TAILORBLEND's vitamin B blend contains all eight B vitamins:
The above quantities are relevant at the recommended dose.
The B vitamins are eight water-soluble nutrients that work as a team. They sit at the centre of energy production, nervous system function, and one of the body's most important biochemical processes: methylation.
What makes this blend different is the form of every ingredient. B6 is supplied as P5P (pyridoxal-5-phosphate), the bioactive form that doesn't require conversion. B9 is methylfolate (5-MTHF), not folic acid — which means it's immediately usable, regardless of MTHFR gene status. B12 is methylcobalamin, the form that plugs directly into the methylation cycle.
This matters because the methylation pathway — which governs gene expression, detoxification, mood chemistry, and cardiovascular health — depends on B2, B6, B9, and B12 working in concert. Variants in the MTHFR gene (common in the general population) reduce the body's ability to activate folate, which can impair methylation and elevate homocysteine. Supplying these vitamins in their active forms bypasses that conversion bottleneck entirely.
Individual dosages sit meaningfully above RDA — this is designed as a practitioner-grade daily complex, not a baseline top-up. B2 at 40mg is particularly relevant for MTHFR support; B6 at 15mg P5P directly supports the transsulfuration pathway, which converts homocysteine onward to glutathione.
For individuals requiring stronger methylation intervention, B9 (methylfolate) can be further increased via an additional methylfolate ingredient add-on in the blend.
In summary: a well-formulated, practitioner-grade B-complex for general methylation support, MTHFR-positive individuals maintaining good status, or anyone looking to do more than cover the basics.
Take daily, with or without food. Best taken in the morning as B vitamins support energy metabolism and may be stimulating for some individuals if taken late in the day.
Suitable for ongoing daily use as a foundational B-complex. Particularly relevant for individuals with known or suspected MTHFR variants, elevated homocysteine, high physiological demand (stress, intense training, poor sleep), or those following plant-based diets where B12 intake from food may be limited.
For targeted methylation support, consider pairing with an additional methylfolate add-on to increase B9 to 800mcg or above.
Biotin at 300mcg may interfere with blood test results. If blood tests are scheduled, discontinue use 48–72 hours prior and inform your healthcare provider.